OptoDBS 2022

June 15-17, 2022

Speakers & Program

Introduction by Christian Lüscher

Session 1 : New Methods and Developments

Mackenzie Mathis – Markerless Pose Estimation

Tommaso Patriarchi – Genetically encoded neuromodulator sensors

Ofer Yizhar – A new generation of bistable GPCR-rhodopsins for pathway-specific modulation of neural circuits

Adam Packer – All-optical interrogation of neuronal excitability during acute focal seizures

Maximilian Scherer – SCG-DBS discrupts pathophysiological network dynamics in TRD

Philip Starr – Mechanisms of DBS in movement disorders : Lesson from chronic invasive brain recording

Session 2 : DBS in Movement Disorders

Grégoire Courtine & Jocelyne Bloch – Optogenetically-inspired neuromodulation therapies for spinal cord injury

Wolf-Julian Neumann – Segregating Direct, Indirect and Hyperdirect Pathways by means of DBS

Gerd Thinkhauser – From temporal dynamics of neurophysiological manifestations toward implementation of adaptive DBS

Alexandra Nelson – Circuit Mechanisms of Parkinson’s Disease in DBS

Nadine Gogolla – Face Expression in Mice

Birte Forstmann – Toward a mechanistic understanding of the human subcortex

Session 3 : DBS of the Basal Ganglia : From Bench to Bedside

Carola Haas – DBS for seizure inference in experimental epilepsy

Andreas Lüthi – Fear Circuits of the Amygdala

Meaghan Creed – Arkypallidal Neurons in Reward

Aryn Gittis – GPe neuromodulation

Asa Mackenzie – Heterogeneity of the subthalamic nucleus (STN)

Roxanne Lofredi – The role of the STN in motor control – DBS

Debora Masini -Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism

Leon Steiner – Synaptic subcortical circuit activations by subthalamic DBS

Nadine Gut – Challenges of DBS for correcting gait and postural deficits – A look into the heterogeneity of midbrain motor circuits

Session 4 : DBS in Clinical & Systems Neuroscience

Esther Florin – Investigating remote DBS effects by MEG

Robert Jech – Investigating remote DBS effects by fMRi

Andreas Horn – Multi-Site Connectomic DBS Modeling in Neurology & Psychiatry

Valerie Voon – Cognitive Models for Neuromodulation in OCD : From Lesions to DBS and Back

Charlotte Piette – Opto-activation of cortical somatostatin interneurons as an alternative therapy in Parkinson’s disease

Olexiy Kochubey – Small changes with large consequences: closely related channelrhodopsin variants in a GABAergic circuit produce different behavioral outcomes

Joshua Gordon – Optogenetic approaches to enhancing connectivity

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