Pathological circuit function is at the origin of many symptoms of neurological and psychiatric disorders. Over the last years, the optogenetic toolbox applied to animal models of behavioral diseases has led to decisive progress yielding blue prints for novel treatments. The challenge is to implement such approaches with current circuit interventions approved for human use such as deep brain stimulation. Optogenetic circuit investigations in rodent models may thus inspire novel rational treatments for diseases without cure.

OptoDBS 2024 will discuss the state of the art of current therapies for DBS and ask how a better understanding of neural circuit dysfunction in pathology could inspire novel protocols. A particular emphasis will be on novel DBS indications such as obsessive compulsive disorders (OCD), depression or addiction. Cutting-edge optogenetic presentations will interleave with clinical studies from leading experts.

The conference will take place at the Campus Biotech, the home many neuroscience groups of EPFL and Unige, as well as the Wyss for Bio and Neuroengeneering. The building is conveniently located within walking distance of the historic center of the city, on the right bank of Lake Geneva, and only 15 minutes from the airport.

We are extremely thankful to the sponsors for their generous support, which has allowed us to have a program with a line-up of distinguished invited speakers. In addition, slots remain available for talks selected from the abstracts.

Students and post-docs are invited to apply for travel awards, again made available by our sponsors.

Looking forward to seeing you soon in Geneva.

Christian Lüscher and Andreas Horn