OptoDBS 2017

June 22-24, 2017

Speakers & Program

Opening remarks by Christian Lüscher

Plenary : Karl Deisseroth – Illuminating next-generation brain therapies

Session 1 : Optogenetic interrogation of BG circuits

Rui Costa – Closed-loop paradigms to investigate action learning and control

Patricia Janak – Stimulus triggers for action : Defining contributions of parallel dopamine-striatal circuits in reward

Ilana Witten – Insight into optoDBS mechanisms from observing neural dynamics

Anna Beyeler – Anatomical and functional diversity in the amygdala

Anna Tchenio – Limiting habenular hyperactivity ameliorates maternal deprivation-driven depressive-like symptoms

Aryn Gittis – Cell-specific pallidal intervention induces long-lasting motor rescue in dopamine depleted mice

Mark Bevan – Plasticity of the subthalamic nucleus in Parkinson’s disease

Session 2 : Mechanism of DBS/Closed loop systems

Andrea Kühn – Pathological network activity in PD and dystonia

Hagai Bergman – Subthalamic synchronized beta oscill

Viviana Gradinaru – Dorsal Raphe Dopamine Neurons Modulate Arousal and Promote Wakefulness Upon Salient Stimuli

Coralie De Hemptinne – Use of electrocorticography to develop closed-loop DBS in Parkinson’s disease

Christelle Baunez – Effects of DBS and optogenetic manipulations of STN on addiction criteria in the rat

Peter Brown – Circuit dynamics and DBS

Yann-Suhan Senova – Assessment of the translational potential of for functional neurosurgery

Jones Parker – Probing the Neural Ensemble Signatures of Therapeutic Efficacy in Parkinson’s Disease

Session 3 : Circuit models of Addiction, OCD, Depression

Nicole Calakos – Striatal Circuit Function in Habit and Compulsion

Damiaan Denys – LFP recording in obsessive compulsive disorder with DBS electrodes

Vikaas Sohal – Prefrontal gamma oscillations and cognitive flexibility

Eric Yttri – Closed-loop photostimulation reveals bidirectional kinetic control in the basal ganglia

Chen-Cheng Zhang – Frontiers of Neuromodulation in China: Addiction, Anorexia Nervosa, Obsessive-Compulsive Disorder and Parkinson’s Disease

Josh Gordon – Adventures in terminal manipulation : do dynamics matter ?

Clement Hamani – DBS for depression : Translational aspects and future perspectives

Session 4 : Techniques & Translation

Jonathan Schor – Towards a Mouse Model for Investigating STN DBS

Polina Anikeeva – Optoelectronic probing of neural circuits with multifunctional fibers

Jerry Vitek – Deep Brain Stimulation Effects on the Basal Ganglia Thalamo-Cortical Circuit

Meaghan Creed – Targeting synaptic plasticity in the reward system to treat addiction-relevant behavior

Michael Bruchas – Modern Approaches for Dissecting Neuromodulatory Circuits in Affective Behaviors

PLENARY : Andreas Lozano – Behavioral and biological effects of deep brain stimulation.

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